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Cancer Clinical Trials

For information about participating in a cancer clinical trial, please contact:

Laura Covolus, RN BS
Research Nurse Coordinator
 
Waseem Cheema, MD
 
Bina Valenzano
 
 

Study

Description

Breast Cancer  

NSABP B-51 - Phase III

Aim: To study women who have cancer cells in the lymph nodes at the time that the breast cancer is diagnosed and have chemotherapy before surgery that clears the cancer cells from the lymph nodes.

This study asks 1) if, after lumpectomy, radiation to the breast and lymph nodes will be better than radiation only to the breast at keeping breast cancer from returning, and 2) if, after mastectomy, radiation to the area where the breast used to be and to the lymph nodes is better than no radiation at keeping breast cancer from returning. 

This study also asks whether giving radiation as described above will help women live longer.

Breast Cancer

MagneMark - Phase I

Aim: To develop a new technique for surgical removal of breast lumps using a magnet rather than a wire, eliminating wire placement and increasing patient comfort.

Breast Cancer

LCCC1410

Aim: To determine if physical activity can affect the levels of a genetic marker of aging in your cells called p16 in patients undergoing chemotherapy for breast cancer.

Breast Cancer

E1Z11

Aim: To increase the understanding of what effects, good and/or bad, that anastrozole has on you and whether your genes can help explain how anastrozole affects you.

 Rectal Cancer    

N1048 - Phase II/III

Aim: To see if radiation can be avoided for a select group of rectal cancer patients who have a good response to 6 treatments with a chemotherapy combination regimen known as FOLFOX.

Colorectal Cancer

Hereditary Colorectal Cancer (HNPCC)

Aim: To evaluate the prevalence and disease features of HNPCC in Asian patients with colon, endometrial and gastric cancer.

Gastrointestinal Cancer

GEJ tumors

A prospective cohort study on Diagnostic prediction and overall survival of patients diagnosed with gastric and gastroesophageal junction (GEJ) tumors in Maimonides Medical Center.

Pancreatic Cancer  

RTOG 0848 - Phase III

Aim: To see if a drug (Erlotinib) along with
chemoradiation can improve outcome for patients with pancreatic cancer.

Head and Neck Cancer

RTOG 0920 - Phase III

Aim: To find out if using a drug (Cetuximab) along with radiation therapy can improve outcomes for patients with head and neck cancer.

Head and Neck Cancer 

NRG-HN001 - Phase II/III

Aim: To see how nasopharyngeal cancer responds to different types or levels of chemotherapy, based on a specific viral marker in the blood, called the Epstein Barr virus, (EBV).

Hematology Oncology

RTOG 0848 - Phase III

Aim: To determine whether chemotherapy is more effective when given with or without erlotinib hydrochloride and/or radiation therapy in treating pancreatic cancer.

Leukemia

InformCLL: A Disease Registry

Aim: To use the information collected to provide information on regimens used to treat chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

Lung Cancer

Alliance 151216 (ALCHEMIST)

Aim: To examine lung cancer patients’ surgically removed tumors for certain genetic changes, and possibly refer there patients to a treatment study (below) with drugs that may specifically target tumors that have these genetic changes.

Lung Cancer

Alliance 081105 - Phase III

 

Aim: To compare any good and bad effects patients may have when treated with the standard treatment against patients who are treated with the standard treatment plus erlotinib (an investigational drug), which targets the EGFR mutation.    

Lung Cancer

E4512 - Phase III

Aim: To compare any good and bad effects of using the study drug, crizotinib (also known as XALKORI®), after completion of surgery and, in some cases, after chemotherapy and/or radiation therapy for ALK-positive non-small cell lung cancer.

Lung Cancer

EA5142 - Phase III

Aim: To find if adding the study drug, Nivolumab (also known as OPDIVO®), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer.

Lymphoma

Communication Skills Intervention to Promote Transition into Survivorship.

Aim: To study and improve the communication skills of doctors who see lymphoma patients.

Radiation Oncology

RTOG 0920 - Phase III

Aim:  This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with cetuximab in treating patients who have undergone surgery for locally advanced head and neck cancer.

ALL Cancer Diagnosis

CAM study

Aim: To study/catalog the types of complementary (alternative) medicine (“CAM”) among patients at Maimonides, in an effort to increase understanding and possibly establish a CAM program at Maimonides.

Renal Cancer

BMS CA209920 Phase 3b/4

Aim: To test the effectiveness, safety, and tolerability of an investigational drug called Nivolumab in combination with ipilimumab (Yervoy) for treatment of advanced Renal Cell Cancer.  Nivolumab is an antibody that is being tested to see if it will allow the body's own immune system to work against tumor cells.