At Maimonides Medical Center, clinical and health services research are integral to advancing clinical care and our clinicians’ participation in academic and scientific activities. Research is a critical complement to the clinical and teaching activities at the Medical Center. Faculty and attending physicians, residents, fellows, and nurses design and conduct research studies that seek to contribute to generalizable knowledge about optimizing clinical care delivery and patient outcomes; evaluating the efficacy of drugs, devices, procedures or diagnostic tests; and assessing various approaches to improving quality and cost efficiency of care. Currently, there are more than 350 active research studies ongoing at Maimonides.
In addition, Maimonides ensures research training program is part of its residency and fellowship programs through the provision of education, technical assistance, mentorship and seed funding for resident-initiated studies. Research professionals at Maimonides have developed online and in-person courses in research education for residents and fellows which address research study design and methodology, participant recruitment and retention, and statistical concepts and analysis. Maimonides also hosts New York State-funded Empire Clinical Research Investigator Program (ECRIP) Research Fellows each year who work closely with faculty mentors on clinical research studies.
Clinicians that engage in research at Maimonides are supported by:
- The Office of Research Administration, which provides administrative and other support to facilitate clinical and health services research.
- A 22-member Institutional Review Board, which meets monthly to review and approve research protocols.
- The Office of Grants and Contracts, which supports investigators in their pursuit of external research funding and post-award grants administration.
- The Maimonides Research and Development Foundation, which provides seed funding for investigator-initiated research.
Overview of Types of Research
Maimonides’ clinicians focus on the following three types of research:
Clinical Research: Patient-oriented research including clinical trials that evaluate the efficacy of drugs, devices or procedures, as well as investigator-initiated studies that test the effectiveness of certain therapies and interventions.
Health Services Research: Evaluation of the organizational factors and delivery approaches that advance quality, reduce cost and improve access to care; outcomes are examined at the individual, family, organizational, community and population level.
Basic Science Research: Laboratory-based research to study biological processes and mechanisms of human disease with a focus on oncology, psychiatry and surgery (breast, orthopedic, vascular).
Institutional Review Board
The Maimonides Institutional Review Board (IRB) is a group of physicians, nurses, pharmacists, research scientists and community members committed to protecting the rights and welfare of human subjects who participate in research studies. The IRB meets monthly to review, discuss and approve human subjects research studies which have the potential to contribute to generalizable scientific knowledge and comply with federal and state laws and regulations, as well as Medical Center policies and standards.
Chair: Edgar Lichstein, MD
Director, Human Research Protections: Kevin Nellis, MS, MT (ASCP), CIP
Clinical Trials and Studies
Maimonides participates in clinical trials that evaluate the efficacy of drugs, devices, and procedures in various departments and divisions, including oncology, cardiology, surgery, emergency medicine and pediatrics. In addition, investigators at Maimonides design and conduct original research projects to address a range of research questions across a number of departments.
The Maimonides Cancer Center is a founding member and leader of the Brooklyn Minority-Based Community Clinical Oncology Program (MBCCOP), funded by the National Cancer Institute (NCI). The purpose of MBCCOP is to bring clinical trials for cancer prevention, control and treatment to the richly diverse population of Brooklyn. MBCCOP’s lead Principal Investigator is Dr. William Solomon, an attending physician in the Division of Hematology-Oncology at the Maimonides Cancer Center. Partners include Kings County Hospital Center and the University Hospital of Brooklyn. More information can be found at www.thebrooklynmbccop.org.
To view a list of active clinical trials at Maimonides, please visit www.clinicaltrials.gov and search for “Maimonides Medical Center”.
Health Services Research
Health services research focuses on evaluating the organizational factors and care delivery approaches which affect quality of care, particularly patient outcomes, access to and cost of care. This type of research examines outcomes at the individual, family, organizational, community and population level. Maimonides contribution to health services research dates back more than ten years.
In 1999, Maimonides evaluated the impact of a care coordination program for congestive heart failure (CHF) patients on hospital readmission rates. The care coordination program involved active identification, tracking and education for CHF patients during and after their hospital visit led by an interdisciplinary care team with nurse practitioners at the Center. CHF readmission rates were measured before and after the intervention and declined from 18% of CHF patients the year before to 6.8% of CHF patients the year after implementation of the care coordination program.
The Safe at Home Program was launched in the Maimonides Division of Geriatric Medicine to assess whether post-discharge home visits by nurse practitioners to elderly patients 75 year and over would reduce 30-day readmission rates. Through this program, Gerontological Nurse Practitioners (GNP) visited elderly patients during their first week post-discharge to conduct medical/geriatric assessments, diagnose and treat acute medical issues, address medication reconciliation, disease education and goals of care, ensure appropriate referrals for homecare and psychosocial needs, and coordinate with primary care providers. Preliminary program data revealed declines in readmission rates after the implementation of the program, when compared with pre-implementation.
With State and private funding, Maimonides is leading an interdisciplinary collaborative of mental health, primary care and social service providers to advance the quality and cost efficiency of care delivered to seriously mentally ill patients in Southwest Brooklyn. This collaborative has designed a unique “mental health home” model of care supported by innovative health information technology tools. These tools will enable providers treating the same patients to share important information such as prescribed medications, receive timely alerts on hospital admissions, and update treatment plans in a coordinated fashion. Maimonides and the collaborative will evaluate this program to determine the impact on reduced admissions, improved outcomes and patient satisfaction with care.
Research and Development Foundation
The Maimonides Research and Development Foundation (R&D Foundation) is a not-for-profit organization supporting the educational, scientific, medical and charitable activities at Maimonides Medical Center. Each year, the R&D Foundation provides seed funding to physicians at Maimonides for investigator-initiated clinical and health services research studies. For Maimonides employees seeking more information on the Foundation, visit the Research section of the Intranet.
Chair: Steve Eisenstadt
President: Howard Minkoff, MD
Executive Assistant: Bernice Rochard
Research Conflict of Interest Policy
Maimonides Medical Center has revised its Research Conflict of Interest policy to comply with new federal regulations, effective August 24, 2012, for researchers who are applying for or have received research funding from the Public Health Service (PHS). Maimonides’ revised policy is available here.